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human pca cell line c4 2b  (ATCC)


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    ATCC human pca cell line c4 2b
    Human Pca Cell Line C4 2b, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 626 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+pca+cell+line+c4+2b/C4-2B/pm41702447-51-8-17
    Average 97 stars, based on 626 article reviews
    human pca cell line c4 2b - by Bioz Stars, 2026-10
    97/100 stars

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    Related Articles

    other:

    Article Title: SNHG18 deficiency reprograms arginine metabolism to foster an immunosuppressive microenvironment in prostate cancer bone metastasis.
    Article Snippet: Advanced prostate cancer (PCa) frequently metastasizes to bone, where the immunosuppressive tumor microenvironment (TME) limits immune checkpoint blockade (ICB) efficacy.. Nevertheless, the molecular mechanisms underlying this immunosuppressive bone TME and bone metastasis (BM) are not yet fully understood.. Analysis of clinical PCa samples, employing in situ hybridization, RT-qPCR, and bioinformatics, demonstrated a progressive downregulation of lncRNA SNHG18 throughout PCa progression, with the lowest expression levels observed in BM associated with poor prognosis.

    Article Title: Enzalutamide combination with Arsenic trioxide suppresses the progression of castration-resistant prostate cancer
    Article Snippet: The human PCa cell line C4-2B was obtained from the American Type Culture Collection (Manassas, VA, USA).

    Cell Culture:

    Article Title: Inhibition of CXCR4 Enhances the Efficacy of Radiotherapy in Metastatic Prostate Cancer Models.
    Article Snippet: The slides were immunostained for CXCR4, CXCR7, and SDF1α, and the relative intensity of staining was analyzed with ImageJ software. .. Human PCa cell line C4-2B was purchased from ATCC and cultured in DMEM/F12 (Lonza) supplemented with 10% FBS. ..

    Article Title: Inhibition of CXCR4 Enhances the Efficacy of Radiotherapy in Metastatic Prostate Cancer Models
    Article Snippet: The slides were immunostained for CXCR4, CXCR7, and SDF1α, and the relative intensity of staining was analyzed with ImageJ software. .. Human PCa cell line C4-2B was purchased from ATCC and cultured in DMEM/F12 (Lonza) supplemented with 10% FBS. ..



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    human pca cell line c4 2b  (ATCC)
    97
    ATCC human pca cell line c4 2b
    Human Pca Cell Line C4 2b, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+pca+cell+line+c4+2b/C4-2B/pm41702447-51-8-17
    Average 97 stars, based on 1 article reviews
    human pca cell line c4 2b - by Bioz Stars, 2026-10
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    human pca cell lines c4 2b  (ATCC)
    97
    ATCC human pca cell lines c4 2b
    Human Pca Cell Lines C4 2b, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+pca+cell+line+c4+2b/C4-2B/pm41656388-31-0-39
    Average 97 stars, based on 1 article reviews
    human pca cell lines c4 2b - by Bioz Stars, 2026-10
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    human pca cell lines  (ATCC)
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    ATCC human pca cell lines
    UFL1 is downregulated in ENZR CRPC. (A) Analysis of UFL1 level in <t>human</t> <t>PCa</t> samples from the TCGA-PRAD dataset. (B) Representative IHC staining images for UFL1 in PCa tissues. (C) Statistical analysis of UFL1 protein levels by IHC. (D) WB examination demonstrating UFL1 protein levels in fresh PCa tumors and paired normal tissues. (E-H) Correlation of UFL1 mRNA level with Gleason score (E), clinical stage (F), lymph node metastasis (G), and distant metastasis (H). (I-J) UFL1 levels in PCa <t>cell</t> <t>lines.</t> LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were procured and examined by qRT-PCR (I) and WB (J). (K) Representative IHC images of UFL1 staining in tumor sections from xenograft mice. (L) UFL1 expression in the public GSE44927 dataset. (M-N) Representative IHC images demonstrating UFL1 level in CSPC and CRPC tissues. (O) Examination of UFL1 expression in human PCa samples from GEO datasets. (P-Q) In the published PCa cohort ( GSE116918 ) and TCGA-PRAD dataset, reduced UFL1 expression was correlated with worse overall survival. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.
    Human Pca Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
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    Average 97 stars, based on 1 article reviews
    human pca cell lines - by Bioz Stars, 2026-10
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    reagents472 human pca cell lines  (ATCC)
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    ATCC reagents472 human pca cell lines
    UFL1 is downregulated in ENZR CRPC. (A) Analysis of UFL1 level in <t>human</t> <t>PCa</t> samples from the TCGA-PRAD dataset. (B) Representative IHC staining images for UFL1 in PCa tissues. (C) Statistical analysis of UFL1 protein levels by IHC. (D) WB examination demonstrating UFL1 protein levels in fresh PCa tumors and paired normal tissues. (E-H) Correlation of UFL1 mRNA level with Gleason score (E), clinical stage (F), lymph node metastasis (G), and distant metastasis (H). (I-J) UFL1 levels in PCa <t>cell</t> <t>lines.</t> LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were procured and examined by qRT-PCR (I) and WB (J). (K) Representative IHC images of UFL1 staining in tumor sections from xenograft mice. (L) UFL1 expression in the public GSE44927 dataset. (M-N) Representative IHC images demonstrating UFL1 level in CSPC and CRPC tissues. (O) Examination of UFL1 expression in human PCa samples from GEO datasets. (P-Q) In the published PCa cohort ( GSE116918 ) and TCGA-PRAD dataset, reduced UFL1 expression was correlated with worse overall survival. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.
    Reagents472 Human Pca Cell Lines, supplied by ATCC, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+pca+cell+line+c4+2b/C4-2B/ppr0956589-162-38-54
    Average 97 stars, based on 1 article reviews
    reagents472 human pca cell lines - by Bioz Stars, 2026-10
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    Image Search Results


    UFL1 is downregulated in ENZR CRPC. (A) Analysis of UFL1 level in human PCa samples from the TCGA-PRAD dataset. (B) Representative IHC staining images for UFL1 in PCa tissues. (C) Statistical analysis of UFL1 protein levels by IHC. (D) WB examination demonstrating UFL1 protein levels in fresh PCa tumors and paired normal tissues. (E-H) Correlation of UFL1 mRNA level with Gleason score (E), clinical stage (F), lymph node metastasis (G), and distant metastasis (H). (I-J) UFL1 levels in PCa cell lines. LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were procured and examined by qRT-PCR (I) and WB (J). (K) Representative IHC images of UFL1 staining in tumor sections from xenograft mice. (L) UFL1 expression in the public GSE44927 dataset. (M-N) Representative IHC images demonstrating UFL1 level in CSPC and CRPC tissues. (O) Examination of UFL1 expression in human PCa samples from GEO datasets. (P-Q) In the published PCa cohort ( GSE116918 ) and TCGA-PRAD dataset, reduced UFL1 expression was correlated with worse overall survival. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Journal: International Journal of Biological Sciences

    Article Title: Loss of UFL1 confers enzalutamide resistance of prostate tumors by regulating METTL16-mediated m6A modification of EEF1A1 mRNA

    doi: 10.7150/ijbs.124214

    Figure Lengend Snippet: UFL1 is downregulated in ENZR CRPC. (A) Analysis of UFL1 level in human PCa samples from the TCGA-PRAD dataset. (B) Representative IHC staining images for UFL1 in PCa tissues. (C) Statistical analysis of UFL1 protein levels by IHC. (D) WB examination demonstrating UFL1 protein levels in fresh PCa tumors and paired normal tissues. (E-H) Correlation of UFL1 mRNA level with Gleason score (E), clinical stage (F), lymph node metastasis (G), and distant metastasis (H). (I-J) UFL1 levels in PCa cell lines. LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were procured and examined by qRT-PCR (I) and WB (J). (K) Representative IHC images of UFL1 staining in tumor sections from xenograft mice. (L) UFL1 expression in the public GSE44927 dataset. (M-N) Representative IHC images demonstrating UFL1 level in CSPC and CRPC tissues. (O) Examination of UFL1 expression in human PCa samples from GEO datasets. (P-Q) In the published PCa cohort ( GSE116918 ) and TCGA-PRAD dataset, reduced UFL1 expression was correlated with worse overall survival. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Article Snippet: Human PCa cell lines (LNCaP and C4-2B) along with HEK293T cells were procured from the American Type Culture Collection (ATCC) and cultured per the supplier's protocols.

    Techniques: Immunohistochemistry, Quantitative RT-PCR, Staining, Expressing

    METTL16 facilitates PCa cell growth, survival, and ENZR. (A) Violin plots illustrating CERES scores for all METTL family members across 11 PCa cell lines. (B) Analysis of METTL16 expression in human PCa samples from GEO datasets. (C) Representative IHC staining images for METTL16 and a statistical graph of METTL16 protein levels. (D) METTL16 expression in PCa cell lines. LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were collected, and total lysates were analyzed by WB (D). (E-J) Cell proliferation assessment utilized CCK-8 assay and colony formation assay in LNCaP-ENZR and C4-2B-ENZR cells following transfection with siNC or METTL16 siRNA. (K-L) Cell viability determination occurred in the designated cell lines during ENZ treatment. LNCaP-ENZR and C4-2B-ENZR cells underwent transfection as specified and received graded ENZ doses over 3 days. Cell viability quantification employed CCK-8 assays. (M-N) Recovery effects of wild-type METTL16 and catalytically inactive METTL16 mutants on METTL16 knockdown-mediated cell proliferation inhibition in LNCaP-ENZR and C4-2B-ENZR cells. (O-P) Cell viability determination in specified cell lines under ENZ treatment. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Journal: International Journal of Biological Sciences

    Article Title: Loss of UFL1 confers enzalutamide resistance of prostate tumors by regulating METTL16-mediated m6A modification of EEF1A1 mRNA

    doi: 10.7150/ijbs.124214

    Figure Lengend Snippet: METTL16 facilitates PCa cell growth, survival, and ENZR. (A) Violin plots illustrating CERES scores for all METTL family members across 11 PCa cell lines. (B) Analysis of METTL16 expression in human PCa samples from GEO datasets. (C) Representative IHC staining images for METTL16 and a statistical graph of METTL16 protein levels. (D) METTL16 expression in PCa cell lines. LNCaP-Parental, LNCaP-ENZR, C4-2B-Parental, and C4-2B-ENZR cells were collected, and total lysates were analyzed by WB (D). (E-J) Cell proliferation assessment utilized CCK-8 assay and colony formation assay in LNCaP-ENZR and C4-2B-ENZR cells following transfection with siNC or METTL16 siRNA. (K-L) Cell viability determination occurred in the designated cell lines during ENZ treatment. LNCaP-ENZR and C4-2B-ENZR cells underwent transfection as specified and received graded ENZ doses over 3 days. Cell viability quantification employed CCK-8 assays. (M-N) Recovery effects of wild-type METTL16 and catalytically inactive METTL16 mutants on METTL16 knockdown-mediated cell proliferation inhibition in LNCaP-ENZR and C4-2B-ENZR cells. (O-P) Cell viability determination in specified cell lines under ENZ treatment. Scale bar, 50 µm. * P < 0.05, ** P < 0.01, *** P < 0.001.

    Article Snippet: Human PCa cell lines (LNCaP and C4-2B) along with HEK293T cells were procured from the American Type Culture Collection (ATCC) and cultured per the supplier's protocols.

    Techniques: Expressing, Immunohistochemistry, CCK-8 Assay, Colony Assay, Transfection, Knockdown, Inhibition